Prognostic significance of cardiac-specific troponins in patients hospitalized for congestive heart failure.

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John Joon-Young You
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January 24, 2010 | History

Prognostic significance of cardiac-specific troponins in patients hospitalized for congestive heart failure.

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Background. The prognostic significance of cardiac-specific troponins in acute heart failure is uncertain.Methods. This retrospective cohort study examined the association between cardiac troponin I and mortality in 2,025 patients newly hospitalized for heart failure in the province of Ontario, Canada.Conclusions. In patients hospitalized for heart failure, increased cardiac troponin I is a powerful and independent predictor of 30-day and 1-year mortality, and can permit early identification of patients with an increased risk of death.Results. Cardiac troponin I greater than 0.5 mug/ml occurred in 699 (34.5%) patients and was associated with higher mortality at 30 days (15.7% versus 6.9%; adjusted odds ratio 1.97; 95% confidence interval, 1.42-2.74; P < 0.001) and 1 year (40.2% versus 26.1%; adjusted odds ratio 1.68; 95% confidence interval, 1.34-2.10; P < 0.001). Increasing levels of cardiac troponin I were associated with progressive increases in 30-day and 1-year mortality (P < 0.001 for trend).

Publish Date
Language
English
Pages
98

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Book Details


Edition Notes

Source: Masters Abstracts International, Volume: 44-02, page: 0815.

Thesis (M.Sc.)--University of Toronto, 2005.

Electronic version licensed for access by U. of T. users.

GERSTEIN MICROTEXT copy on microfiche (2 microfiches).

The Physical Object

Pagination
98 leaves.
Number of pages
98

ID Numbers

Open Library
OL19217149M
ISBN 10
0494073195

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January 24, 2010 Edited by WorkBot add more information to works
December 11, 2009 Created by WorkBot add works page