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January 24, 2010 | History

Formation of a cartilage-biomaterial biphasic construct with a calcified cartilage zone 1 edition

Formation of a cartilage-biomaterial biphasic construct with a calcifi ...
Katherine Sarah Allan

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Formation of a cartilage-biomaterial biphasic construct with a calcified cartilage zone.

Published 2005 .
Written in English.

About the Book

This study describes the development of a biphasic construct in which the hyaline cartilage has calcified cartilage close to the tissue-substrate interface. The mineral that formed in vitro was identified as hydroxyapatite and was similar to that found in vivo. The inclusion of mineralized cartilage within the extracellular matrix significantly improved the load-bearing capacity, tissue stiffness and attachment to the underlying substrate when compared to cartilage lacking a mineralized component. Understanding the mechanical properties of the cartilage-bone interface will provide valuable insight into the necessary conditions for forming suitable biphasic constructs in vitro that can be used to successfully resurface osteochondral defects.

Edition Notes

Source: Masters Abstracts International, Volume: 44-01, page: 0512.

Thesis (M.A.Sc.)--University of Toronto, 2005.

Electronic version licensed for access by U. of T. users.

GERSTEIN MICROTEXT copy on microfiche (2 microfiches).

The Physical Object

129 leaves.
Number of pages

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History Created December 11, 2009 · 2 revisions Download catalog record: RDF / JSON

January 24, 2010 Edited by WorkBot add more information to works
December 11, 2009 Created by WorkBot add works page