MARC Record from marc_columbia

LEADER: 03998cam a2200469 i 4500
001 15134276
005 20220326232832.0
006 m o d
007 cr cnu|||unuuu
008 180824t20192019flua ob 001 0 eng d
035 $a(OCoLC)on1049800275
035 $a(NNC)15134276
040 $aN$T$beng$erda$epn$cN$T$dN$T$dMERER$dOCLCF$dOCLCQ$dQGQ$dOCLCQ$dOCLCO
020 $a9780429955402$q(electronic bk.)
020 $a0429955405$q(electronic bk.)
020 $z9781444179637
035 $a(OCoLC)1049800275
050 4 $aRM847
072 7 $aMED$x071000$2bisacsh
082 04 $a615.842$223
049 $aZCUA
245 00 $aBasic clinical radiobiology /$cedited by Michael C. Joiner, Albert J. van der Kogel.
264 1 $aBoca Raton, FL :$bCRC Press,$c[2019]
264 4 $c©2019
300 $a1 online resource
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
504 $aIncludes bibliographical references and index.
588 0 $aOnline resource; title from PDF title page (EBSCO, viewed August 27, 2018).
520 $a"[This book] is a concise but comprehensive textbook setting out the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology, clinical radiation physics, and radiation technology. Fully revised and updated to keep abreast of current developments in radiation biology and radiation oncology, this fifth edition continues to present in an interesting way the biological basis of radiation therapy, discussing the basic principles and significant developments that underlie the latest attempts to improve the radiotherapeutic management of cancer. This new edition is highly illustrated with attractive 2-colour presentation and now includes new chapters on stem cells, tissue response and the convergence of radiotherapy, radiobiology, and physics. It will be invaluable for FRCR (clinical oncology) and equivalent candidates, SpRs (and equivalent) in radiation oncology, practicing radiation oncologists and radiotherapists, as well as radiobiologists and radiotherapy physicists."--Website ebook/publisher
505 0 $aIntroduction: The significance of radiobiology and radiotherapy for cancer treatment -- Irradiation-induced damage and the DNA damage response -- Cell death after irradiation: How, when and why cells die -- Quantifying cell kill and cell survival -- Radiation dose-response relationships -- Linear energy transfer and relative biological effectiveness -- Physics of radiation therapy for the radiobiologist -- Tumour growth and response to radiation -- Fractionation: The linear-quadratic approach -- The linear-quadratic approach in clinical practice -- Modified fractionation -- Time factors in normal tissue responses to irradiation -- The dose-rate effect -- Pathogenesis of normal tissue side effects -- Stem cells in radiotherapy -- Normal tissue tolerance and the effect of dose inhomogeneities -- The oxygen effect and therapeutic approaches to tumour hypoxia -- The tumour microenvironment and cellular hypoxia responses -- Combined radiotherapy and chemotherapy -- Molecular targeted agents for enhancing tumour response -- Biological individualisation of radiotherapy -- Molecular image guided radiotherapy -- Retreatment tolerance of normal tissues -- Biological response modification of normal tissue reactions: Basic principles and pitfalls -- Hadron therapy: The clinical aspects -- Tissue response models -- Second cancers after radiotherapy
650 0 $aRadiobiology.
650 2 $aRadiobiology
650 6 $aRadiobiologie.
650 7 $aMEDICAL$xPharmacology.$2bisacsh
650 7 $aRadiobiology.$2fast$0(OCoLC)fst01088040
655 4 $aElectronic books.
700 1 $aJoiner, Michael,$eeditor.
700 1 $aKogel, Albert van der,$eeditor.
856 40 $uhttp://www.columbia.edu/cgi-bin/cul/resolve?clio15134276$zTaylor & Francis eBooks
852 8 $blweb$hEBOOKS