{"first_sentence": {"type": "/type/text", "value": "The large-scale use of animals in research began in the early and middle decades of the last century when, mainly in Germany and France, the rapid advances in physiology were made."}, "physical_format": "Hardcover", "subtitle": "Selection and Handling of Animals in Biomedical Research", "last_modified": {"type": "/type/datetime", "value": "2008-04-29 15:03:11.581851"}, "languages": [{"key": "/l/eng"}], "type": {"key": "/type/edition"}, "publishers": ["CRC-Press"], "number_of_pages": 2, "isbn_13": ["9780849343780"], "id": 11183386, "edition_name": "1 edition", "isbn_10": ["084934378X"], "publish_date": "August 2, 1994", "key": "/b/OL8260392M", "title": "Handbook of Laboratory Animal Science", "contributions": ["Per Svendsen (Editor)", "Jann Hau (Editor)"], "subjects": ["Medical research", "Veterinary science: laboratory animals", "Mammals", "Animals", "Science/Mathematics", "Laboratory Medicine", "Science / Zoology", "Animal models in research", "Animal experimentation", "Laboratory Animals"], "revision": 1}